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3CSY

Crystal structure of the trimeric prefusion Ebola virus glycoprotein in complex with a neutralizing antibody from a human survivor

3CSY の概要
エントリーDOI10.2210/pdb3csy/pdb
分子名称Fab KZ52 heavy chain, Fab KZ52 light chain, Envelope glycoprotein GP1, ... (8 entities in total)
機能のキーワードglycoprotein-antibody complex, immune system-viral protein complex, immune system/viral protein
由来する生物種Homo sapiens (human)
詳細
細胞内の位置GP2: Virion membrane; Single-pass type I membrane protein. GP1: Virion membrane; Peripheral membrane protein. GP2-delta: Secreted: Q05320
GP2: Virion membrane; Single-pass type I membrane protein (By similarity). GP1: Virion membrane; Peripheral membrane protein (By similarity). GP2-delta: Secreted (By similarity): P87666
タンパク質・核酸の鎖数16
化学式量合計406070.53
構造登録者
Lee, J.E.,Fusco, M.L.,Hessell, A.J.,Oswald, W.B.,Burton, D.R.,Saphire, E.O. (登録日: 2008-04-10, 公開日: 2008-07-08, 最終更新日: 2021-10-20)
主引用文献Lee, J.E.,Fusco, M.L.,Hessell, A.J.,Oswald, W.B.,Burton, D.R.,Saphire, E.O.
Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor.
Nature, 454:177-182, 2008
Cited by
PubMed: 18615077
DOI: 10.1038/nature07082
主引用文献が同じPDBエントリー
実験手法
X-RAY DIFFRACTION (3.4 Å)
構造検証レポート
Validation report summary of 3csy
検証レポート(詳細版)ダウンロードをダウンロード

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件を2024-03-27に公開中

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