3CSY
Crystal structure of the trimeric prefusion Ebola virus glycoprotein in complex with a neutralizing antibody from a human survivor
3CSY の概要
エントリーDOI | 10.2210/pdb3csy/pdb |
分子名称 | Fab KZ52 heavy chain, Fab KZ52 light chain, Envelope glycoprotein GP1, ... (8 entities in total) |
機能のキーワード | glycoprotein-antibody complex, immune system-viral protein complex, immune system/viral protein |
由来する生物種 | Homo sapiens (human) 詳細 |
細胞内の位置 | GP2: Virion membrane; Single-pass type I membrane protein. GP1: Virion membrane; Peripheral membrane protein. GP2-delta: Secreted: Q05320 GP2: Virion membrane; Single-pass type I membrane protein (By similarity). GP1: Virion membrane; Peripheral membrane protein (By similarity). GP2-delta: Secreted (By similarity): P87666 |
タンパク質・核酸の鎖数 | 16 |
化学式量合計 | 406070.53 |
構造登録者 | Lee, J.E.,Fusco, M.L.,Hessell, A.J.,Oswald, W.B.,Burton, D.R.,Saphire, E.O. (登録日: 2008-04-10, 公開日: 2008-07-08, 最終更新日: 2021-10-20) |
主引用文献 | Lee, J.E.,Fusco, M.L.,Hessell, A.J.,Oswald, W.B.,Burton, D.R.,Saphire, E.O. Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor. Nature, 454:177-182, 2008 Cited by PubMed: 18615077DOI: 10.1038/nature07082 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (3.4 Å) |
構造検証レポート
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