3CS8

Structural and Biochemical Basis for the Binding Selectivity of PPARg to PGC-1a

Summary for 3CS8

Entry DOI	10.2210/pdb3cs8/pdb
Descriptor	Peroxisome proliferator-activated receptor gamma, PGC-1alfa peptide, SULFATE ION, ... (5 entities in total)
Functional Keywords	coactivator, nuclear receptor, alternative splicing, diabetes mellitus, disease mutation, dna-binding, metal-binding, nucleus, obesity, phosphoprotein, polymorphism, transcription, transcription regulation, zinc, zinc-finger, rna-binding, nuclear protein
Biological source	Homo sapiens More
Cellular location	Nucleus: P37231 Q9UBK2
Total number of polymer chains	2
Total formula weight	33296.64
Authors	Li, Y.,Martynowski, D. (deposition date: 2008-04-09, release date: 2008-06-03, Last modification date: 2024-02-21)
Primary citation	Li, Y.,Kovach, A.,Suino-Powell, K.,Martynowski, D.,Xu, H.E. Structural and biochemical basis for the binding selectivity of peroxisome proliferator-activated receptor gamma to PGC-1alpha. J.Biol.Chem., 283:19132-19139, 2008 Cited by PubMed: 18469005 DOI: 10.1074/jbc.M802040200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation