3CS8

Structural and Biochemical Basis for the Binding Selectivity of PPARg to PGC-1a

3CS8 の概要

• エントリーDOI: 10.2210/pdb3cs8/pdb
• 分子名称: Peroxisome proliferator-activated receptor gamma, PGC-1alfa peptide, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: coactivator, nuclear receptor, alternative splicing, diabetes mellitus, disease mutation, dna-binding, metal-binding, nucleus, obesity, phosphoprotein, polymorphism, transcription, transcription regulation, zinc, zinc-finger, rna-binding, nuclear protein
• 由来する生物種: Homo sapiens; 詳細
• 細胞内の位置: Nucleus: P37231 Q9UBK2
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 33296.64

構造登録者

Li, Y.,Martynowski, D. (登録日: 2008-04-09, 公開日: 2008-06-03, 最終更新日: 2024-02-21)

• 主引用文献: Li, Y.,Kovach, A.,Suino-Powell, K.,Martynowski, D.,Xu, H.E.; Structural and biochemical basis for the binding selectivity of peroxisome proliferator-activated receptor gamma to PGC-1alpha.; J.Biol.Chem., 283:19132-19139, 2008; PubMed: 18469005; DOI: 10.1074/jbc.M802040200

実験手法

X-RAY DIFFRACTION (2.3 Å)