3CRH
Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ser and Lys101Ala
Summary for 3CRH
Entry DOI | 10.2210/pdb3crh/pdb |
Related | 3CRG 3CRI |
Descriptor | Heparin-binding growth factor 1, SULFATE ION (3 entities in total) |
Functional Keywords | crystal packing, angiogenesis, developmental protein, differentiation, growth factor, heparin-binding, mitogen, hormone |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted: P05230 |
Total number of polymer chains | 2 |
Total formula weight | 33653.53 |
Authors | Meher, A.K.,Honjo, E.,Kuroki, R.,Lee, J.,Somasundaram, T.,Blaber, M. (deposition date: 2008-04-07, release date: 2009-02-17, Last modification date: 2024-02-21) |
Primary citation | Meher, A.K.,Blaber, S.I.,Lee, J.,Honjo, E.,Kuroki, R.,Blaber, M. Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1. Acta Crystallogr.,Sect.F, 65:1136-1140, 2009 Cited by PubMed: 19923735DOI: 10.1107/S1744309109036987 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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