3CPW
The structure of the antibiotic LINEZOLID bound to the large ribosomal subunit of HALOARCULA MARISMORTUI
Summary for 3CPW
Entry DOI | 10.2210/pdb3cpw/pdb |
Descriptor | 23S RIBOSOMAL RNA, 50S ribosomal protein L10e, 50S ribosomal protein L13P, ... (40 entities in total) |
Functional Keywords | linezolid, 50s ribosomal subunit, antibiotic complexes, ribonucleoprotein, ribosomal protein, rna-binding, rrna-binding, trna-binding, metal-binding, zinc-finger, ribosome |
Biological source | HALOARCULA MARISMORTUI More |
Cellular location | Cytoplasm : P12743 |
Total number of polymer chains | 31 |
Total formula weight | 1474423.98 |
Authors | Ippolito, J.A.,Kanyo, Z.K.,Wang, D.,Franceschi, F.J.,Moore, P.B.,Steitz, T.A.,Duffy, E.M. (deposition date: 2008-04-01, release date: 2008-07-22, Last modification date: 2024-02-21) |
Primary citation | Ippolito, J.A.,Kanyo, Z.K.,Wang, D.,Franceschi, F.J.,Moore, P.B.,Steitz, T.A.,Duffy, E.M. Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit J.Med.Chem., 51:3353-3356, 2008 Cited by PubMed: 18494460DOI: 10.1021/jm800379d PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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