3CPW

The structure of the antibiotic LINEZOLID bound to the large ribosomal subunit of HALOARCULA MARISMORTUI

3CPW の概要

• エントリーDOI: 10.2210/pdb3cpw/pdb
• 分子名称: 23S RIBOSOMAL RNA, 50S ribosomal protein L10e, 50S ribosomal protein L13P, ... (40 entities in total)
• 機能のキーワード: linezolid, 50s ribosomal subunit, antibiotic complexes, ribonucleoprotein, ribosomal protein, rna-binding, rrna-binding, trna-binding, metal-binding, zinc-finger, ribosome
• 由来する生物種: HALOARCULA MARISMORTUI; 詳細
• 細胞内の位置: Cytoplasm : P12743
• タンパク質・核酸の鎖数: 31
• 化学式量合計: 1474423.98

構造登録者

Ippolito, J.A.,Kanyo, Z.K.,Wang, D.,Franceschi, F.J.,Moore, P.B.,Steitz, T.A.,Duffy, E.M. (登録日: 2008-04-01, 公開日: 2008-07-22, 最終更新日: 2024-02-21)

• 主引用文献: Ippolito, J.A.,Kanyo, Z.K.,Wang, D.,Franceschi, F.J.,Moore, P.B.,Steitz, T.A.,Duffy, E.M.; Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit; J.Med.Chem., 51:3353-3356, 2008; PubMed: 18494460; DOI: 10.1021/jm800379d

実験手法

X-RAY DIFFRACTION (2.7 Å)