3CON

Crystal structure of the human NRAS GTPase bound with GDP

3CON の概要

• エントリーDOI: 10.2210/pdb3con/pdb
• 分子名称: GTPase NRas, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
• 機能のキーワード: structural genomics consortium, sgc, gtpase, gdp, oncogene, disease mutation, golgi apparatus, gtp-binding, lipoprotein, membrane, methylation, nucleotide-binding, palmitate, prenylation, proto-oncogene, hydrolase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cell membrane ; Lipid-anchor ; Cytoplasmic side : P01111
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 22312.04

構造登録者

Nedyalkova, L.,Tong, Y.,Tempel, W.,Shen, L.,Loppnau, P.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Bochkarev, A.,Park, H.,Structural Genomics Consortium (SGC) (登録日: 2008-03-28, 公開日: 2008-04-08, 最終更新日: 2023-08-30)

• 主引用文献: Nedyalkova, L.,Tong, Y.,Tempel, W.,Shen, L.,Loppnau, P.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Bochkarev, A.,Park, H.; Crystal structure of the human NRAS GTPase bound with GDP.; To be Published,

実験手法

X-RAY DIFFRACTION (1.649 Å)