3COA
Crystal Structure of FoxO1 DBD Bound to IRE DNA
Summary for 3COA
Entry DOI | 10.2210/pdb3coa/pdb |
Related | 3CO6 3CO7 |
Descriptor | DNA (5'-D(*DTP*DGP*DGP*DTP*DTP*DTP*DGP*DTP*DTP*DTP*DTP*DGP*DCP*DTP*DTP*DG)-3'), DNA (5'-D(*DCP*DAP*DAP*DGP*DCP*DAP*DAP*DAP*DAP*DCP*DAP*DAP*DAP*DCP*DCP*DA)-3'), Forkhead box protein O1, ... (5 entities in total) |
Functional Keywords | winged helix, forkhead domain, chromosomal rearrangement, cytoplasm, dna-binding, nucleus, phosphoprotein, proto-oncogene, transcription, transcription regulation, transcription-dna complex, transcription/dna |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm : Q12778 |
Total number of polymer chains | 6 |
Total formula weight | 45976.46 |
Authors | Brent, M.M.,Anand, R.,Marmorstein, R. (deposition date: 2008-03-27, release date: 2008-09-16, Last modification date: 2024-02-21) |
Primary citation | Brent, M.M.,Anand, R.,Marmorstein, R. Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification. Structure, 16:1407-1416, 2008 Cited by PubMed: 18786403DOI: 10.1016/j.str.2008.06.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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