3CL0
N1 Neuraminidase H274Y + oseltamivir
Summary for 3CL0
Entry DOI | 10.2210/pdb3cl0/pdb |
Related | 3CKZ 3CL2 |
Descriptor | Neuraminidase, (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | n1, neuraminidase, h274y, oseltamivir, glycosidase, hydrolase, membrane, transmembrane, virion, viral protein |
Biological source | Influenza A virus (A/Viet Nam/1203/2004(H5N1)) |
Total number of polymer chains | 1 |
Total formula weight | 42534.37 |
Authors | Collins, P.,Haire, L.F.,Lin, Y.P.,Liu, J.,Russell, R.J.,Walker, P.A.,Skehel, J.J.,Martin, S.R.,Hay, A.J.,Gamblin, S.J. (deposition date: 2008-03-18, release date: 2008-05-20, Last modification date: 2018-08-22) |
Primary citation | Collins, P.J.,Haire, L.F.,Lin, Y.P.,Liu, J.,Russell, R.J.,Walker, P.A.,Skehel, J.J.,Martin, S.R.,Hay, A.J.,Gamblin, S.J. Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants. Nature, 453:1258-1261, 2008 Cited by PubMed: 18480754DOI: 10.1038/nature06956 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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