3CL0
N1 Neuraminidase H274Y + oseltamivir
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Neuraminidase | polymer | 385 | 42209.9 | 1 | UniProt (Q6DPL2) Pfam (PF00064) In PDB | Influenza A virus (A/Viet Nam/1203/2004(H5N1)) | |
| 2 | A | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid | non-polymer | 284.4 | 1 | Chemie (G39) | |||
| 3 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 4 | water | water | 18.0 | 175 | Chemie (HOH) |
Sequence modifications
A: 83 - 468 (UniProt: Q6DPL2)
| PDB | External Database | Details |
|---|---|---|
| Tyr 252 | His 233 | conflict |
| Tyr 274 | His 255 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42209.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 324.4 | |
| All* | Total formula weight | 42534.4 |
