3CDZ
Crystal structure of human factor VIII
Summary for 3CDZ
Entry DOI | 10.2210/pdb3cdz/pdb |
Descriptor | Coagulation factor VIII heavy chain, Coagulation factor VIII light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | blood clotting, blood coagulation, cofactor, factor viii, refacto, acute phase, disease mutation, glycoprotein, hemophilia, metal-binding, secreted, sulfation |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 167247.95 |
Authors | Ngo, J.C.,Huang, M.,Roth, D.A.,Furie, B.C.,Furie, B. (deposition date: 2008-02-27, release date: 2008-04-01, Last modification date: 2023-08-30) |
Primary citation | Ngo, J.C.,Huang, M.,Roth, D.A.,Furie, B.C.,Furie, B. Crystal structure of human factor VIII: implications for the formation of the factor IXa-factor VIIIa complex. Structure, 16:597-606, 2008 Cited by PubMed: 18400180DOI: 10.1016/j.str.2008.03.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.98 Å) |
Structure validation
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