3CDZ

Crystal structure of human factor VIII

3CDZ の概要

• エントリーDOI: 10.2210/pdb3cdz/pdb
• 分子名称: Coagulation factor VIII heavy chain, Coagulation factor VIII light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: blood clotting, blood coagulation, cofactor, factor viii, refacto, acute phase, disease mutation, glycoprotein, hemophilia, metal-binding, secreted, sulfation
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 167247.95

構造登録者

Ngo, J.C.,Huang, M.,Roth, D.A.,Furie, B.C.,Furie, B. (登録日: 2008-02-27, 公開日: 2008-04-01, 最終更新日: 2023-08-30)

• 主引用文献: Ngo, J.C.,Huang, M.,Roth, D.A.,Furie, B.C.,Furie, B.; Crystal structure of human factor VIII: implications for the formation of the factor IXa-factor VIIIa complex.; Structure, 16:597-606, 2008; PubMed: 18400180; DOI: 10.1016/j.str.2008.03.001

実験手法

X-RAY DIFFRACTION (3.98 Å)