3C5F

Structure of a binary complex of the R517A Pol lambda mutant

Summary for 3C5F

• Entry DOI: 10.2210/pdb3c5f/pdb
• Related: 3C5G
• Descriptor: DNA (5'-D(*DCP*DGP*DGP*DCP*DCP*DGP*DTP*DAP*DCP*DTP*DG)-3'), DNA (5'-D(*DCP*DAP*DGP*DTP*DAP*DC)-3'), DNA (5'-D(P*DGP*DCP*DCP*DG)-3'), ... (6 entities in total)
• Functional Keywords: helix hairpin helix, dna damage, dna repair, dna replication, dna synthesis, dna-binding, dna-directed dna polymerase, lyase, manganese, metal-binding, nucleotidyltransferase, nucleus, phosphoprotein, polymorphism, transferase, lyase-dna complex, lyase/dna
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : Q9UGP5
• Total number of polymer chains: 8
• Total formula weight: 87595.65

Authors

Garcia-Diaz, M.,Bebenek, K.,Foley, M.C.,Pedersen, L.C.,Schlick, T.,Kunkel, T.A. (deposition date: 2008-01-31, release date: 2008-09-02, Last modification date: 2021-10-20)

• Primary citation: Bebenek, K.,Garcia-Diaz, M.,Foley, M.C.,Pedersen, L.C.,Schlick, T.,Kunkel, T.A.; Substrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase lambda.; Embo Rep., 9:459-464, 2008; PubMed: 18369368; DOI: 10.1038/embor.2008.33

Experimental method

X-RAY DIFFRACTION (2.25 Å)