3C59

Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain

3C59 の概要

• エントリーDOI: 10.2210/pdb3c59/pdb
• 関連するPDBエントリー: 3C5T
• 分子名称: Glucagon-like peptide 1 receptor, Exendin-4, decyl 4-O-alpha-D-glucopyranosyl-1-thio-beta-D-glucopyranoside, ... (4 entities in total)
• 機能のキーワード: ligand-bound g protein-coupled receptor, g-protein coupled receptor, glycoprotein, membrane, transducer, transmembrane, amidation, cleavage on pair of basic residues, secreted, signaling protein-signaling protein complex, signaling protein/signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cell membrane ; Multi- pass membrane protein : P43220; Secreted: P26349
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 18310.06

構造登録者

Runge, S. (登録日: 2008-01-31, 公開日: 2008-02-19, 最終更新日: 2018-05-23)

• 主引用文献: Runge, S.,Thogersen, H.,Madsen, K.,Lau, J.,Rudolph, R.; Crystal Structure of the Ligand-bound Glucagon-like Peptide-1 Receptor Extracellular Domain; J.Biol.Chem., 283:11340-11347, 2008; PubMed: 18287102; DOI: 10.1074/jbc.M708740200

実験手法

X-RAY DIFFRACTION (2.3 Å)