3C2Y

tRNA-Guanine Transglycosylase (TGT) in complex with 6-Amino-2-methyl-1,7-dihydro-imidazo[4,5-g]quinazolin-8-one

3C2Y の概要

• エントリーDOI: 10.2210/pdb3c2y/pdb
• 関連するPDBエントリー: 2BBF 2Z7K 3C2N 3C2Z
• 分子名称: Queuine tRNA-ribosyltransferase, ZINC ION, 6-amino-2-methyl-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, ... (5 entities in total)
• 機能のキーワード: transferase, tim barrel, glycosyltransferase, metal-binding, queuosine biosynthesis, trna processing
• 由来する生物種: Zymomonas mobilis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43666.79

構造登録者

Ritschel, T.,Heine, A.,Klebe, G. (登録日: 2008-01-26, 公開日: 2009-02-03, 最終更新日: 2023-11-01)

• 主引用文献: Ritschel, T.,Hoertner, S.,Heine, A.,Diederich, F.,Klebe, G.; Crystal structure analysis and in silico pKa calculations suggest strong pKa shifts of ligands as driving force for high-affinity binding to TGT; Chembiochem, 10:716-727, 2009; PubMed: 19199329; DOI: 10.1002/cbic.200800782

実験手法

X-RAY DIFFRACTION (1.78 Å)