3BT2

Structure of urokinase receptor, urokinase and vitronectin complex

Summary for 3BT2

• Entry DOI: 10.2210/pdb3bt2/pdb
• Related: 2fd6 3BT1
• Descriptor: Urokinase-type plasminogen activator, Vitronectin, anti-uPAR antibody, light chain, ... (8 entities in total)
• Functional Keywords: protein-protein interaction, glycoprotein, gpi-anchor, lipoprotein, membrane, receptor, secreted, blood coagulation, egf-like domain, fibrinolysis, hydrolase, kringle, phosphoprotein, plasminogen activation, protease, serine protease, zymogen, cell adhesion, heparin-binding, sulfation, immunoglobulin domain, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 98915.33

Authors

Huang, M. (deposition date: 2007-12-27, release date: 2008-03-25, Last modification date: 2023-11-01)

• Primary citation: Huai, Q.,Zhou, A.,Lin, L.,Mazar, A.P.,Parry, G.C.,Callahan, J.,Shaw, D.E.,Furie, B.,Furie, B.C.,Huang, M.; Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes; Nat.Struct.Mol.Biol., 15:422-423, 2008; PubMed: 18376415; DOI: 10.1038/nsmb.1404

Experimental method

X-RAY DIFFRACTION (2.5 Å)