3BT2
Structure of urokinase receptor, urokinase and vitronectin complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Urokinase-type plasminogen activator | polymer | 135 | 15359.3 | 1 | UniProt (P00749) Pfam (PF00051) | Homo sapiens (human) | uPA, U-plasminogen activator |
| 2 | B (B) | Vitronectin | polymer | 40 | 4573.1 | 1 | UniProt (P04004) Pfam (PF01033) | Homo sapiens (human) | Serum-spreading factor, S-protein, V75 |
| 3 | C (L) | anti-uPAR antibody, light chain | polymer | 212 | 23269.7 | 1 | Mus musculus (house mouse) | ||
| 4 | D (H) | anti-uPAR antibody, heavy chain | polymer | 214 | 23041.7 | 1 | Mus musculus (house mouse) | ||
| 5 | E (U) | Urokinase plasminogen activator surface receptor | polymer | 283 | 31601.5 | 1 | UniProt (Q03405) Pfam (PF00021) | Homo sapiens (human) | uPAR, U-PAR, Monocyte activation antigen Mo3, CD87 antigen |
| 6 | F, G (C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 7 | H (U) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 8 | I, J, K, L (A, L, H, U) | water | water | 18.0 | 57 | Chemie (HOH) |
Sequence modifications
A: 1 - 133 (UniProt: P00749)
U: 1 - 281 (UniProt: Q03405)
| PDB | External Database | Details |
|---|---|---|
| Arg -1 | - | expression tag |
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Arg 0 | - | expression tag |
| Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 97845.3 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 98915.3 |
