3BN3

crystal structure of ICAM-5 in complex with aL I domain

3BN3 の概要

• エントリーDOI: 10.2210/pdb3bn3/pdb
• 分子名称: Integrin alpha-L, Intercellular adhesion molecule 5, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: icam-5, i domain, integrin, allosteric mobility, cell adhesion, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 44165.56

構造登録者

Zhang, H.,Springer, T.A.,Wang, J.-h. (登録日: 2007-12-13, 公開日: 2008-08-19, 最終更新日: 2023-08-30)

• 主引用文献: Zhang, H.,Casasnovas, J.M.,Jin, M.,Liu, J.H.,Gahmberg, C.G.,Springer, T.A.,Wang, J.-h.; An unusual allosteric mobility of the C-terminal helix of a high-affinity alpha L integrin I domain variant bound to ICAM-5; Mol.Cell, 31:432-437, 2008; PubMed: 18691975; DOI: 10.1016/j.molcel.2008.06.022

実験手法

X-RAY DIFFRACTION (2.099 Å)