3BKM
Structure of anti-amyloid-beta Fab WO2 (Form A, P212121)
Summary for 3BKM
Entry DOI | 10.2210/pdb3bkm/pdb |
Related | 3BAE 3BKC 3BKJ |
Descriptor | WO2 IgG2a Fab fragment Light Chain Kappa, WO2 IgG2a Fab fragment Heavy Chain, SODIUM ION, ... (5 entities in total) |
Functional Keywords | abeta, amyloid beta peptide, fab, wo2, alzheimer's disease, immunotherapies, app, immune system |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 52362.16 |
Authors | Miles, L.A.,Wun, K.S.,Crespi, G.A.,Fodero-Tavoletti, M.,Galatis, D.,Bageley, C.J.,Beyreuther, K.,Masters, C.L.,Cappai, R.,McKinstry, W.J.,Barnham, K.J.,Parker, M.W. (deposition date: 2007-12-07, release date: 2008-04-15, Last modification date: 2023-11-01) |
Primary citation | Miles, L.A.,Wun, K.S.,Crespi, G.A.,Fodero-Tavoletti, M.T.,Galatis, D.,Bagley, C.J.,Beyreuther, K.,Masters, C.L.,Cappai, R.,McKinstry, W.J.,Barnham, K.J.,Parker, M.W. Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope. J.Mol.Biol., 377:181-192, 2008 Cited by PubMed: 18237744DOI: 10.1016/j.jmb.2007.12.036 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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