3BK3

Crystal structure of the complex of BMP-2 and the first Von Willebrand domain type C of Crossveinless-2

3BK3 の概要

• エントリーDOI: 10.2210/pdb3bk3/pdb
• 関連するPDBエントリー: 1REW 2H62 2H64
• 分子名称: Bone morphogenetic protein 2, Crossveinless 2 (3 entities in total)
• 機能のキーワード: tgf-beta superfamily, bmp modulator proteins, chordin, bmp inhibitor, chondrogenesis, cleavage on pair of basic residues, cytokine, developmental protein, differentiation, glycoprotein, growth factor, osteogenesis, polymorphism, secreted, hormone-growth factor complex, hormone/growth factor
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Secreted: P12643
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 40136.38

構造登録者

Mueller, T.D.,Sebald, W.,Zhang, J.-L. (登録日: 2007-12-05, 公開日: 2008-05-27, 最終更新日: 2021-11-10)

• 主引用文献: Zhang, J.-L.,Qiu, L.-Y.,Kotzsch, A.,Weidauer, S.,Patterson, L.,Hammerschmidt, M.,Sebald, W.,Mueller, T.D.; Crystal structure analysis reveals how the Chordin family member crossveinless 2 blocks BMP-2 receptor binding; Dev.Cell, 14:739-750, 2008; PubMed: 18477456; DOI: 10.1016/j.devcel.2008.02.017

実験手法

X-RAY DIFFRACTION (2.7 Å)