3BHH

Crystal structure of human calcium/calmodulin-dependent protein kinase IIB isoform 1 (CAMK2B)

3BHH の概要

• エントリーDOI: 10.2210/pdb3bhh/pdb
• 分子名称: Calcium/calmodulin-dependent protein kinase type II beta chain, [4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-6-(methylamino)pyrimidin-2-yl}amino)phenyl]acetonitrile (3 entities in total)
• 機能のキーワード: camk2b, cam2, camk2, cam kinase ii beta chain, camk ii beta subunit, calcium/calmodulion dependent protein kinase ii beta, ec:2.7.1.123, mgc29528, proline rich calmodulin dependent protein kinase, structural genomics consortium, sgc, atp-binding, calmodulin-binding, nucleotide-binding, phosphoprotein, serine/threonine-protein kinase, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 134979.33

構造登録者

Filippakopoulos, P.,Rellos, P.,Niesen, F.,Burgess, N.,Bullock, A.,Berridge, G.,Pike, A.C.W.,Ugochukwu, E.,Pilka, E.S.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2007-11-28, 公開日: 2007-12-11, 最終更新日: 2023-08-30)

• 主引用文献: Filippakopoulos, P.,Rellos, P.,Niesen, F.,Burgess, N.,Bullock, A.,Berridge, G.,Pike, A.C.W.,Ugochukwu, E.,Pilka, E.S.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Knapp, S.; Crystal Structure of Human Calcium/Calmodulin-Dependent Protein Kinase IIB Isoform 1 (CAMK2B).; To be Published,

実験手法

X-RAY DIFFRACTION (2.4 Å)