3BEC
Crystal structure of E. coli penicillin-binding protein 5 in complex with a peptide-mimetic cephalosporin
Summary for 3BEC
Entry DOI | 10.2210/pdb3bec/pdb |
Related | 3BEB |
Descriptor | Penicillin-binding protein 5, GLYCEROL, (2R)-2-[(R)-{[(6S)-6-amino-6-carboxyhexanoyl]amino}(carboxy)methyl]-5-methyl-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, ... (4 entities in total) |
Functional Keywords | peptidoglycan synthesis, penicillin-binding protein, dd-carboxypeptidase, hydrolase, designed cephalosporin, cell shape, cell wall biogenesis/degradation, inner membrane, membrane, protease |
Biological source | Escherichia coli |
Cellular location | Cell inner membrane; Peripheral membrane protein; Cytoplasmic side: P0AEB2 |
Total number of polymer chains | 1 |
Total formula weight | 40598.92 |
Authors | Powell, A.J.,Davies, C. (deposition date: 2007-11-16, release date: 2008-08-26, Last modification date: 2023-08-30) |
Primary citation | Sauvage, E.,Powell, A.J.,Heilemann, J.,Josephine, H.R.,Charlier, P.,Davies, C.,Pratt, R.F. Crystal structures of complexes of bacterial DD-peptidases with peptidoglycan-mimetic ligands: the substrate specificity puzzle J.Mol.Biol., 381:383-393, 2008 Cited by PubMed: 18602645DOI: 10.1016/j.jmb.2008.06.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
Download full validation report