3BDJ

Crystal Structure of Bovine Milk Xanthine Dehydrogenase with a Covalently Bound Oxipurinol Inhibitor

Summary for 3BDJ

Entry DOI	10.2210/pdb3bdj/pdb
Descriptor	Xanthine dehydrogenase/oxidase, CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, ... (10 entities in total)
Functional Keywords	oxypurinol, oxipurinol, alloxanthine, allopurinol, covalently bound inhibitor, xanthine oxidase, xanthine oxidoreductase, xanthine dehydrogenase, fad, flavoprotein, iron-sulfur, molybdopterin, peroxisome, oxidoreductase
Biological source	Bos taurus (Bovine)
Cellular location	Cytoplasm (By similarity): P80457
Total number of polymer chains	2
Total formula weight	298490.44
Authors	Eger, B.T.,Okamoto, K.,Nishino, T.,Pai, E.F.,Nishino, T. (deposition date: 2007-11-14, release date: 2008-11-25, Last modification date: 2023-08-30)
Primary citation	Okamoto, K.,Eger, B.T.,Nishino, T.,Pai, E.F.,Nishino, T. Mechanism of inhibition of xanthine oxidoreductase by allopurinol: crystal structure of reduced bovine milk xanthine oxidoreductase bound with oxipurinol. Nucleosides Nucleotides Nucleic Acids, 27:888-893, 2008 Cited by PubMed: 18600558 DOI: 10.1080/15257770802146577 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation