3B8X

Crystal structure of GDP-4-keto-6-deoxymannose-3-dehydratase (ColD) H188N mutant with bound GDP-perosamine

Summary for 3B8X

Entry DOI	10.2210/pdb3b8x/pdb
Related	2GMU 2R0T
Descriptor	Pyridoxamine 5-phosphate-dependent dehydrase, SODIUM ION, [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S,5S,6R)-3,4-dihydroxy-5-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-6-methyltetrahydro-2H-pyran-2-yl dihydrogen diphosphate, ... (5 entities in total)
Functional Keywords	aspartate aminotransferase, colitose, perosamine, o-antigen, plp, pyridoxal phosphate, transferase
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	90665.87
Authors	Cook, P.D.,Holden, H.M. (deposition date: 2007-11-02, release date: 2007-11-27, Last modification date: 2023-08-30)
Primary citation	Cook, P.D.,Holden, H.M. GDP-4-Keto-6-deoxy-D-mannose 3-Dehydratase, Accommodating a Sugar Substrate in the Active Site. J.Biol.Chem., 283:4295-4303, 2008 Cited by PubMed: 18045869 DOI: 10.1074/jbc.M708893200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation