2R0T

Crystal structure of GDP-4-keto-6-deoxymannose-3-dehydratase with a trapped PLP-glutamate geminal diamine

Summary for 2R0T

Entry DOI	10.2210/pdb2r0t/pdb
Related	2GMS 2GMU
Descriptor	Pyridoxamine 5-phosphate-dependent dehydrase, N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-L-glutamic acid (3 entities in total)
Functional Keywords	colitose, aspartate aminotransferase, geminal diamine, pyridoxal phosphate, transferase
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	89443.45
Authors	Cook, P.D.,Holden, H.M. (deposition date: 2007-08-21, release date: 2007-12-18, Last modification date: 2023-08-30)
Primary citation	Cook, P.D.,Holden, H.M. A Structural Study of GDP-4-Keto-6-Deoxy-d-Mannose-3-Dehydratase: Caught in the Act of Geminal Diamine Formation Biochemistry, 46:14215-14224, 2007 Cited by PubMed: 17997582 DOI: 10.1021/bi701686s PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation