3B7D

Crystal structure of the GLUR2 ligand binding core (HS1S2J) in complex with CNQX at 2.5 A resolution

Summary for 3B7D

• Entry DOI: 10.2210/pdb3b7d/pdb
• Related: 1FTJ 1FTL 1FTM 1FTO
• Descriptor: Glutamate receptor 2, 7-nitro-2,3-dioxo-2,3-dihydroquinoxaline-6-carbonitrile (3 entities in total)
• Functional Keywords: s1s2, cnqx, structural genomics, psi-2, protein structure initiative, center for structures of membrane proteins, csmp, cell junction, glycoprotein, ion transport, ionic channel, lipoprotein, palmitate, phosphorylation, postsynaptic cell membrane, receptor, rna editing, synapse, transmembrane, transport, membrane protein
• Biological source: Rattus norvegicus (Norway rat); More
• Cellular location: Cell membrane; Multi-pass membrane protein: P19491
• Total number of polymer chains: 8
• Total formula weight: 234461.52

Authors

Hays, F.A.,Center for Structures of Membrane Proteins (CSMP) (deposition date: 2007-10-30, release date: 2007-11-20, Last modification date: 2023-08-30)

• Primary citation: Menuz, K.,Stroud, R.M.,Nicoll, R.A.,Hays, F.A.; TARP auxiliary subunits switch AMPA receptor antagonists into partial agonists.; Science, 318:815-817, 2007; PubMed: 17975069; DOI: 10.1126/science.1146317

Experimental method

X-RAY DIFFRACTION (2.5 Å)