3B7D

Crystal structure of the GLUR2 ligand binding core (HS1S2J) in complex with CNQX at 2.5 A resolution

3B7D の概要

• エントリーDOI: 10.2210/pdb3b7d/pdb
• 関連するPDBエントリー: 1FTJ 1FTL 1FTM 1FTO
• 分子名称: Glutamate receptor 2, 7-nitro-2,3-dioxo-2,3-dihydroquinoxaline-6-carbonitrile (3 entities in total)
• 機能のキーワード: s1s2, cnqx, structural genomics, psi-2, protein structure initiative, center for structures of membrane proteins, csmp, cell junction, glycoprotein, ion transport, ionic channel, lipoprotein, palmitate, phosphorylation, postsynaptic cell membrane, receptor, rna editing, synapse, transmembrane, transport, membrane protein
• 由来する生物種: Rattus norvegicus (Norway rat); 詳細
• 細胞内の位置: Cell membrane; Multi-pass membrane protein: P19491
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 234461.52

構造登録者

Hays, F.A.,Center for Structures of Membrane Proteins (CSMP) (登録日: 2007-10-30, 公開日: 2007-11-20, 最終更新日: 2023-08-30)

• 主引用文献: Menuz, K.,Stroud, R.M.,Nicoll, R.A.,Hays, F.A.; TARP auxiliary subunits switch AMPA receptor antagonists into partial agonists.; Science, 318:815-817, 2007; PubMed: 17975069; DOI: 10.1126/science.1146317

実験手法

X-RAY DIFFRACTION (2.5 Å)