3B6W

Crystal Structure of the GLUR2 Ligand Binding Core (S1S2J) T686S Mutant in Complex with Glutamate at 1.7 Resolution

3B6W の概要

• エントリーDOI: 10.2210/pdb3b6w/pdb
• 関連するPDBエントリー: 1FTJ 1FTO 1P1U 3B6Q 3B6T
• 分子名称: Glutamate receptor 2, SULFATE ION, GLUTAMIC ACID, ... (4 entities in total)
• 機能のキーワード: glur2, t686s, mutant, ampa receptor, ionotropic glutamate receptor, alternative splicing, cell junction, glycoprotein, ion transport, ionic channel, lipoprotein, membrane, palmitate, phosphorylation, postsynaptic cell membrane, rna editing, synapse, transmembrane, transport, membrane protein
• 由来する生物種: Rattus norvegicus (Norway rat); 詳細
• 細胞内の位置: Cell membrane; Multi-pass membrane protein: P19491
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 117509.14

構造登録者

Cho, Y.,Lolis, E.,Howe, J.R. (登録日: 2007-10-29, 公開日: 2008-02-05, 最終更新日: 2021-10-20)

• 主引用文献: Zhang, W.,Cho, Y.,Lolis, E.,Howe, J.R.; Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating.; J.Neurosci., 28:932-943, 2008; PubMed: 18216201; DOI: 10.1523/JNEUROSCI.3309-07.2008

実験手法

X-RAY DIFFRACTION (1.7 Å)