3B2Z
Crystal Structure of ADAMTS4 (apo form)
Summary for 3B2Z
Entry DOI | 10.2210/pdb3b2z/pdb |
Descriptor | ADAMTS-4, ZINC ION, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | metalloprotease, aggrecanase, cleavage on pair of basic residues, extracellular matrix, glycoprotein, hydrolase, metal-binding, secreted, zymogen |
Biological source | Homo sapiens (human) |
Cellular location | Secreted, extracellular space, extracellular matrix (By similarity): O75173 |
Total number of polymer chains | 8 |
Total formula weight | 274937.80 |
Authors | Mosyak, L.,Stahl, M.,Somers, W. (deposition date: 2007-10-19, release date: 2007-12-25, Last modification date: 2023-08-30) |
Primary citation | Mosyak, L.,Georgiadis, K.,Shane, T.,Svenson, K.,Hebert, T.,McDonagh, T.,Mackie, S.,Olland, S.,Lin, L.,Zhong, X.,Kriz, R.,Reifenberg, E.L.,Collins-Racie, L.A.,Corcoran, C.,Freeman, B.,Zollner, R.,Marvell, T.,Vera, M.,Sum, P.E.,Lavallie, E.R.,Stahl, M.,Somers, W. Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5. Protein Sci., 17:16-21, 2008 Cited by PubMed: 18042673DOI: 10.1110/ps.073287008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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