3AZB

Beta-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Plasmodium falciparum in complex with NAS91-11

Summary for 3AZB

Entry DOI	10.2210/pdb3azb/pdb
Related	1Z6B 1ZHG 3AZ8 3AZ9 3AZA
Descriptor	Beta-hydroxyacyl-ACP dehydratase, GLYCEROL, 5-chloro-8-[(3-chlorobenzyl)oxy]quinoline, ... (4 entities in total)
Functional Keywords	hot dog fold, fabz, beta-hydroxyacyl acyl carrier protein dehydratase, lyase, acyl carrier protein, lyase-inhibitor complex, lyase/inhibitor
Biological source	Plasmodium falciparum
Total number of polymer chains	24
Total formula weight	411559.68
Authors	Maity, K.,Venkata, B.S.,Kapoor, N.,Surolia, N.,Surolia, A.,Suguna, K. (deposition date: 2011-05-21, release date: 2012-02-29, Last modification date: 2023-11-01)
Primary citation	Maity, K.,Venkata, B.S.,Kapoor, N.,Surolia, N.,Surolia, A.,Suguna, K. Structural basis for the functional and inhibitory mechanisms of beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Plasmodium falciparum J.Struct.Biol., 176:238-249, 2011 Cited by PubMed: 21843645 DOI: 10.1016/j.jsb.2011.07.018 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation