3AZB
Beta-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Plasmodium falciparum in complex with NAS91-11
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016836 | molecular_function | hydro-lyase activity |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0016836 | molecular_function | hydro-lyase activity |
| C | 0006633 | biological_process | fatty acid biosynthetic process |
| C | 0016836 | molecular_function | hydro-lyase activity |
| D | 0006633 | biological_process | fatty acid biosynthetic process |
| D | 0016836 | molecular_function | hydro-lyase activity |
| E | 0006633 | biological_process | fatty acid biosynthetic process |
| E | 0016836 | molecular_function | hydro-lyase activity |
| F | 0006633 | biological_process | fatty acid biosynthetic process |
| F | 0016836 | molecular_function | hydro-lyase activity |
| G | 0006633 | biological_process | fatty acid biosynthetic process |
| G | 0016836 | molecular_function | hydro-lyase activity |
| H | 0006633 | biological_process | fatty acid biosynthetic process |
| H | 0016836 | molecular_function | hydro-lyase activity |
| I | 0006633 | biological_process | fatty acid biosynthetic process |
| I | 0016836 | molecular_function | hydro-lyase activity |
| J | 0006633 | biological_process | fatty acid biosynthetic process |
| J | 0016836 | molecular_function | hydro-lyase activity |
| K | 0006633 | biological_process | fatty acid biosynthetic process |
| K | 0016836 | molecular_function | hydro-lyase activity |
| L | 0006633 | biological_process | fatty acid biosynthetic process |
| L | 0016836 | molecular_function | hydro-lyase activity |
| M | 0006633 | biological_process | fatty acid biosynthetic process |
| M | 0016836 | molecular_function | hydro-lyase activity |
| N | 0006633 | biological_process | fatty acid biosynthetic process |
| N | 0016836 | molecular_function | hydro-lyase activity |
| O | 0006633 | biological_process | fatty acid biosynthetic process |
| O | 0016836 | molecular_function | hydro-lyase activity |
| P | 0006633 | biological_process | fatty acid biosynthetic process |
| P | 0016836 | molecular_function | hydro-lyase activity |
| Q | 0006633 | biological_process | fatty acid biosynthetic process |
| Q | 0016836 | molecular_function | hydro-lyase activity |
| R | 0006633 | biological_process | fatty acid biosynthetic process |
| R | 0016836 | molecular_function | hydro-lyase activity |
| S | 0006633 | biological_process | fatty acid biosynthetic process |
| S | 0016836 | molecular_function | hydro-lyase activity |
| T | 0006633 | biological_process | fatty acid biosynthetic process |
| T | 0016836 | molecular_function | hydro-lyase activity |
| U | 0006633 | biological_process | fatty acid biosynthetic process |
| U | 0016836 | molecular_function | hydro-lyase activity |
| V | 0006633 | biological_process | fatty acid biosynthetic process |
| V | 0016836 | molecular_function | hydro-lyase activity |
| W | 0006633 | biological_process | fatty acid biosynthetic process |
| W | 0016836 | molecular_function | hydro-lyase activity |
| X | 0006633 | biological_process | fatty acid biosynthetic process |
| X | 0016836 | molecular_function | hydro-lyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 1 |
| Chain | Residue |
| A | PRO101 |
| A | PRO128 |
| B | PRO101 |
| B | PHE129 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE KM1 D 1 |
| Chain | Residue |
| D | PRO97 |
| D | HIS98 |
| D | ALA150 |
| D | GLN151 |
| D | GLY154 |
| D | ASN167 |
| D | PHE169 |
| D | LEU170 |
| D | PHE171 |
| D | PHE226 |
| C | HIS133 |
| C | PHE134 |
| C | PRO141 |
| C | GLY142 |
| D | LEU96 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL D 2 |
| Chain | Residue |
| C | PRO101 |
| C | PRO128 |
| D | PRO101 |
| D | PHE129 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL E 3 |
| Chain | Residue |
| E | PRO101 |
| E | PRO128 |
| E | PHE129 |
| F | PRO101 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE KM1 G 2 |
| Chain | Residue |
| G | HIS98 |
| G | ALA150 |
| G | GLY154 |
| G | ASN167 |
| G | PHE169 |
| G | LEU170 |
| G | PHE171 |
| G | PHE226 |
| H | HIS133 |
| H | PHE134 |
| H | ILE139 |
| H | MET140 |
| H | PRO141 |
| H | GLY142 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL G 4 |
| Chain | Residue |
| G | PRO101 |
| G | PRO128 |
| H | PRO128 |
| site_id | AC7 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE KM1 H 3 |
| Chain | Residue |
| G | HIS133 |
| G | PHE134 |
| G | ILE139 |
| G | PRO141 |
| G | GLY142 |
| H | HIS98 |
| H | GLU147 |
| H | ALA150 |
| H | GLY154 |
| H | ASN167 |
| H | LEU168 |
| H | PHE169 |
| H | PHE171 |
| H | PHE226 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL I 5 |
| Chain | Residue |
| I | PRO101 |
| I | PHE102 |
| I | PHE129 |
| I | HOH577 |
| J | PRO101 |
| site_id | AC9 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE KM1 J 4 |
| Chain | Residue |
| I | HIS133 |
| I | PHE134 |
| I | ILE139 |
| I | GLY142 |
| J | HIS98 |
| J | GLU147 |
| J | ALA150 |
| J | GLN151 |
| J | GLY154 |
| J | ASN167 |
| J | PHE169 |
| J | PHE171 |
| J | PHE226 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL K 6 |
| Chain | Residue |
| K | PRO101 |
| K | PRO128 |
| L | PRO101 |
| L | PRO128 |
| L | PHE129 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL M 7 |
| Chain | Residue |
| M | PRO101 |
| M | PHE102 |
| M | LEU144 |
| N | PRO128 |
| N | PHE129 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL O 8 |
| Chain | Residue |
| O | PRO101 |
| O | PHE102 |
| O | PRO128 |
| P | PRO128 |
| P | PHE129 |
| site_id | BC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE KM1 P 5 |
| Chain | Residue |
| P | ALA150 |
| P | GLY154 |
| P | ASN167 |
| P | PHE169 |
| P | LEU170 |
| P | PHE171 |
| P | PHE226 |
| O | HIS133 |
| O | PHE134 |
| O | ILE139 |
| O | MET140 |
| O | PRO141 |
| O | GLY142 |
| P | HIS98 |
| P | GLU147 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL Q 9 |
| Chain | Residue |
| Q | PRO101 |
| Q | PRO128 |
| R | PRO101 |
| R | PRO128 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL S 10 |
| Chain | Residue |
| S | PRO101 |
| S | PHE102 |
| S | PHE129 |
| T | PRO101 |
| T | PHE102 |
| T | LEU144 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL V 11 |
| Chain | Residue |
| U | PRO101 |
| U | PRO128 |
| V | PRO101 |
| V | PHE129 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL X 12 |
| Chain | Residue |
| W | PRO101 |
| X | PRO101 |
| X | PRO128 |
| X | PHE129 |
