3AT4
Crystal structure of CK2alpha with pyradine derivertive
Summary for 3AT4
| Entry DOI | 10.2210/pdb3at4/pdb |
| Related | 3AT2 3AT3 |
| Descriptor | Casein kinase II subunit alpha, [1-(6-{6-[(1-methylethyl)amino]-1H-indazol-1-yl}pyrazin-2-yl)-1H-pyrrol-3-yl]acetic acid (3 entities in total) |
| Functional Keywords | ck2, kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 40854.60 |
| Authors | Kinoshita, T. (deposition date: 2010-12-23, release date: 2011-11-09, Last modification date: 2023-11-01) |
| Primary citation | Kinoshita, T.,Sekiguchi, Y.,Fukada, H.,Nakaniwa, T.,Tada, T.,Nakamura, S.,Kitaura, K.,Ohno, H.,Suzuki, Y.,Hirasawa, A.,Nakanishi, I.,Tsujimoto, G. A detailed thermodynamic profile of cyclopentyl and isopropyl derivatives binding to CK2 kinase Mol.Cell.Biochem., 356:97-105, 2011 Cited by PubMed: 21735094DOI: 10.1007/s11010-011-0960-9 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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