Calcium pump crystal structure with bound TNP-AMP and TG

Summary for 3AR5

Related2AGV 2DQS 2ZBD 3AR2 3AR3 3AR4 3AR6 3AR7 3AR8 3AR9
DescriptorSarcoplasmic/endoplasmic reticulum calcium ATPase 1, SODIUM ION, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, 4ALPHA, 6BETA, 6ABETA, 7BETA, 8ALPHA(Z), 9BALPHA]]-6-(ACETYLOXY)-2,3,-3A,4,5,6,6A,7,8,9B-DECAHYDRO-3,3A-DIHYDROXY-3,6,9-TRIMETHYL-8-[(2-METHYL-1-OXO-2-BUTENYL)OXY]-2-OXO-4-(1-OXOBUTOXY)-AZULENO[4,5-B]FURAN-7-YL ESTER, ... (6 entities in total)
Functional Keywordsp-type atpase, hydrolase, calcium transport, calcium binding, atp binding, endoplasmic reticulum, sarcoplasmic reticulum, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceOryctolagus cuniculus (rabbits)
Cellular locationEndoplasmic reticulum membrane; Multi-pass membrane protein P04191
Total number of polymer chains1
Total molecular weight113062.79
Toyoshima, C.,Yonekura, S.,Tsueda, J.,Iwasawa, S. (deposition date: 2010-11-24, release date: 2011-02-02, Last modification date: 2013-07-31)
Primary citation
Toyoshima, C.,Yonekura, S.,Tsueda, J.,Iwasawa, S.
Trinitrophenyl derivatives bind differently from parent adenine nucleotides to Ca2+-ATPase in the absence of Ca2+
Proc.Natl.Acad.Sci.USA, 108:1833-1838, 2011
PubMed: 21239683 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1017659108
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2729 0.6% 6.7% 9.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-21