3ANL

Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) complexed with pyridin-2-ylmethylphosphonic acid

3ANL の概要

関連するPDBエントリー2EGH 1T1R 1T1S 1JVS 3ANM 3ANN
分子名称1-deoxy-D-xylulose 5-phosphate reductoisomerase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (pyridin-2-ylmethyl)phosphonic acid, ... (4 entities in total)
機能のキーワードreductoisomerase, nadph binding, oxidoreductase
由来する生物種Escherichia coli
ポリマー鎖数2
分子量合計93329.8
構造登録者
Endo, K.,Kato, M.,Deng, L.,Song, Y.,Yajima, S. (登録日: 2010-09-03, 公開日: 2011-02-23, 最終更新日: 2011-10-19)
主引用文献
Deng, L.,Endo, K.,Kato, M.,Cheng, G.,Yajima, S.,Song, Y.
Structures of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase/Lipophilic Phosphonate Complexes
ACS Med Chem Lett, 2:165-170, 2011
PubMed: 21379374 (主引用文献が同じPDBエントリー)
DOI: 10.1021/ml100243r
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.1 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.227100.4%7.0%5.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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