3ANL
Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) complexed with pyridin-2-ylmethylphosphonic acid
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | polymer | 420 | 45746.4 | 2 | UniProt (P45568) Pfam (PF02670) Pfam (PF08436) Pfam (PF13288) In PDB | Escherichia coli | DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase |
2 | A, B | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
3 | A, B | (pyridin-2-ylmethyl)phosphonic acid | non-polymer | 173.1 | 2 | Chemie (SYC) | |||
4 | water | water | 18.0 | 413 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 397 (UniProt: P45568)
PDB | External Database | Details |
---|---|---|
Met -10 | - | expression tag |
Arg -9 | - | expression tag |
Gly -8 | - | expression tag |
Ser -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
Gly 0 | - | expression tag |
Ser 398 | - | expression tag |
Ala 399 | - | expression tag |
Cys 400 | - | expression tag |
Asp 401 | - | expression tag |
Leu 402 | - | expression tag |
Gly 403 | - | expression tag |
Thr 404 | - | expression tag |
Pro 405 | - | expression tag |
Gly 406 | - | expression tag |
Arg 407 | - | expression tag |
Pro 408 | - | expression tag |
Ala 409 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 91492.8 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1837.1 | |
All* | Total formula weight | 93329.8 |