3A6P

Crystal structure of Exportin-5:RanGTP:pre-miRNA complex

3A6P の概要

• エントリーDOI: 10.2210/pdb3a6p/pdb
• 分子名称: Exportin-5, 13-mer peptide, GTP-binding nuclear protein Ran, ... (7 entities in total)
• 機能のキーワード: exportin-5, pre-microrna, rangtp, nuclearexport, importin-beta family, nucleus, phosphoprotein, protein transport, rna-binding, rna-mediated gene silencing, transport, trna-binding, cell cycle, cell division, gtp-binding, isopeptide bond, mitosis, nucleotide-binding, protein transport-nuclear protein-rna complex, protein transport/nuclear protein/rna
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Nucleus : Q9HAV4 P62825
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 355861.69

構造登録者

Okada, C.,Yamashita, E.,Lee, S.J.,Shibata, S.,Katahira, J.,Nakagawa, A.,Yoneda, Y.,Tsukihara, T. (登録日: 2009-09-07, 公開日: 2009-12-08, 最終更新日: 2012-04-25)

• 主引用文献: Okada, C.,Yamashita, E.,Lee, S.J.,Shibata, S.,Katahira, J.,Nakagawa, A.,Yoneda, Y.,Tsukihara, T.; A high-resolution structure of the pre-microRNA nuclear export machinery; Science, 326:1275-1279, 2009; PubMed: 19965479; DOI: 10.1126/science.1178705

実験手法

X-RAY DIFFRACTION (2.92 Å)