3A4U
Crystal structure of MCFD2 in complex with carbohydrate recognition domain of ERGIC-53
Summary for 3A4U
Entry DOI | 10.2210/pdb3a4u/pdb |
Descriptor | Protein ERGIC-53, Multiple coagulation factor deficiency protein 2, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | lectin, ergic, er, golgi, transport, disulfide bond, endoplasmic reticulum, er-golgi transport, golgi apparatus, membrane, protein transport, transmembrane, disease mutation |
Biological source | Homo sapiens (human) More |
Cellular location | Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein: P49257 Endoplasmic reticulum-Golgi intermediate compartment : Q8NI22 |
Total number of polymer chains | 2 |
Total formula weight | 44884.60 |
Authors | Nishio, M.,Kamiya, Y.,Mizushima, T.,Wakatsuki, S.,Sasakawa, H.,Yamamoto, K.,Uchiyama, S.,Noda, M.,McKay, A.R.,Fukui, K.,Hauri, H.P.,Kato, K. (deposition date: 2009-07-17, release date: 2010-01-05, Last modification date: 2023-11-01) |
Primary citation | Nishio, M.,Kamiya, Y.,Mizushima, T.,Wakatsuki, S.,Sasakawa, H.,Yamamoto, K.,Uchiyama, S.,Noda, M.,McKay, A.R.,Fukui, K.,Hauri, H.P.,Kato, K. Structural basis for the cooperative interplay between the two causative gene products of combined factor V and factor VIII deficiency. Proc.Natl.Acad.Sci.USA, 107:4034-4039, 2010 Cited by PubMed: 20142513DOI: 10.1073/pnas.0908526107 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.84 Å) |
Structure validation
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