3A4O

Lyn kinase domain

Summary for 3A4O

Entry DOI	10.2210/pdb3a4o/pdb
Descriptor	Tyrosine-protein kinase Lyn, STAUROSPORINE (2 entities in total)
Functional Keywords	src family, kinase domain, alternative splicing, atp-binding, host-virus interaction, kinase, lipoprotein, myristate, nucleotide-binding, palmitate, phosphoprotein, polymorphism, proto-oncogene, transferase, tyrosine-protein kinase
Biological source	Homo sapiens (human)
Cellular location	Cell membrane: P07948
Total number of polymer chains	1
Total formula weight	33461.35
Authors	Miyano, N.,Kinoshita, T.,Tada, T. (deposition date: 2009-07-11, release date: 2009-12-08, Last modification date: 2023-11-01)
Primary citation	Miyano, N.,Kinoshita, T.,Nakai, R.,Kirii, Y.,Yokota, K.,Tada, T. Structural basis for the inhibitor recognition of human Lyn kinase domain Bioorg.Med.Chem.Lett., 19:6557-6560, 2009 Cited by PubMed: 19857964 DOI: 10.1016/j.bmcl.2009.10.038 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation