3A4G

Structure of cytochrome P450 vdh from Pseudonocardia autotrophica (trigonal crystal form)

Summary for 3A4G

• Entry DOI: 10.2210/pdb3a4g/pdb
• Related: 3A4H 3A4Z 3A50 3A51
• Descriptor: Vitamin D hydroxylase, PROTOPORPHYRIN IX CONTAINING FE, 2-(2-METHOXYETHOXY)ETHANOL, ... (4 entities in total)
• Functional Keywords: cytochrome p450, vitamin d3 hydroxylase, hemoprotein, monooxygenase, oxidoreductase
• Biological source: Pseudonocardia autotrophica
• Cellular location: Cytoplasm : C4B644
• Total number of polymer chains: 1
• Total formula weight: 46224.24

Authors

Yasutake, Y.,Fujii, Y.,Cheon, W.K.,Arisawa, A.,Tamura, T. (deposition date: 2009-07-07, release date: 2010-07-14, Last modification date: 2023-11-01)

• Primary citation: Yasutake, Y.,Fujii, Y.,Nishioka, T.,Cheon, W.K.,Arisawa, A.,Tamura, T.; Structural evidence for enhancement of sequential vitamin D3 hydroxylation activities by directed evolution of cytochrome P450 vitamin D3 hydroxylase; J.Biol.Chem., 285:31193-31201, 2010; PubMed: 20667833; DOI: 10.1074/jbc.M110.147009

Experimental method

X-RAY DIFFRACTION (1.75 Å)