3A1B
Crystal structure of the DNMT3A ADD domain in complex with histone H3
Summary for 3A1B
Entry DOI | 10.2210/pdb3a1b/pdb |
Related | 3A1A |
Descriptor | DNA (cytosine-5)-methyltransferase 3A, Histone H3.1, ZINC ION, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | zinc-finger, histone binding, chromosomal protein, dna damage, dna repair, dna-binding, methylation, nucleosome core, nucleus, phosphoprotein, alternative promoter usage, metal-binding, methyltransferase, s-adenosyl-l-methionine, transferase |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus : Q9Y6K1 |
Total number of polymer chains | 1 |
Total formula weight | 18703.51 |
Authors | Otani, J.,Arita, K.,Ariyoshi, M.,Shirakawa, M. (deposition date: 2009-03-28, release date: 2009-11-10, Last modification date: 2023-11-01) |
Primary citation | Otani, J.,Nankumo, T.,Arita, K.,Inamoto, S.,Ariyoshi, M.,Shirakawa, M. Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain Embo Rep., 10:1235-1241, 2009 Cited by PubMed: 19834512DOI: 10.1038/embor.2009.218 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.292 Å) |
Structure validation
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