3A1B

Crystal structure of the DNMT3A ADD domain in complex with histone H3

3A1B の概要

• エントリーDOI: 10.2210/pdb3a1b/pdb
• 関連するPDBエントリー: 3A1A
• 分子名称: DNA (cytosine-5)-methyltransferase 3A, Histone H3.1, ZINC ION, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: zinc-finger, histone binding, chromosomal protein, dna damage, dna repair, dna-binding, methylation, nucleosome core, nucleus, phosphoprotein, alternative promoter usage, metal-binding, methyltransferase, s-adenosyl-l-methionine, transferase
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Nucleus : Q9Y6K1
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 18703.51

構造登録者

Otani, J.,Arita, K.,Ariyoshi, M.,Shirakawa, M. (登録日: 2009-03-28, 公開日: 2009-11-10, 最終更新日: 2023-11-01)

• 主引用文献: Otani, J.,Nankumo, T.,Arita, K.,Inamoto, S.,Ariyoshi, M.,Shirakawa, M.; Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain; Embo Rep., 10:1235-1241, 2009; PubMed: 19834512; DOI: 10.1038/embor.2009.218

実験手法

X-RAY DIFFRACTION (2.292 Å)