3ZI3

Crystal structure of the B24His-insulin - human analogue

Summary for 3ZI3
DescriptorINSULIN, SULFATE ION, ... (4 entities in total)
Functional Keywordshormone
Biological sourceHOMO SAPIENS (HUMAN)
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Cellular locationSecreted: P01308 P01308
Total number of polymer chains2
Total formula weight5904.69
Authors
Zakova, L.,Kletvikova, E.,Veverka, V.,Lepsik, M.,Watson, C.J.,Turkenburg, J.P.,Jiracek, J.,Brzozowski, A.M. (deposition date: 2013-01-02, release date: 2013-03-06, Last modification date: 2013-05-01)
Primary citationBrzozowski, A.M.,Jiracek, J.,Kletvikova, E.,Lepsik, M.,Turkenburg, J.P.,Veverka, V.,Watson, C.J.,Zakova, L.
Structural Integrity of the B24 Site in Human Insulin is Important for Hormone Functionality
J.Biol.Chem., 288:10230-, 2013
PubMed: 23447530
DOI: 110.1074/JBC.M112.448050
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation
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PDB entries from 2021-06-23