3X1H

hPPARgamma Ligand binding domain in complex with 5-oxo-tricosahexaenoic acid

Summary for 3X1H

• Entry DOI: 10.2210/pdb3x1h/pdb
• Related: 3X1I
• Descriptor: Peroxisome proliferator-activated receptor gamma, (7E,11Z,14Z,17Z,20Z)-5-oxotricosa-7,11,14,17,20-pentaenoic acid (3 entities in total)
• Functional Keywords: nuclear receptor, transcription regulation, ligand binding domain, diabetes mellitus, zinc-finger, dna-binding, transcription, obesity
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: P37231
• Total number of polymer chains: 2
• Total formula weight: 63616.07

Authors

Egawa, D.,Itoh, T.,Yamamoto, K. (deposition date: 2014-11-18, release date: 2015-04-08, Last modification date: 2022-08-24)

• Primary citation: Egawa, D.,Itoh, T.,Yamamoto, K.; Characterization of covalent bond formation between PPAR gamma and oxo-fatty acids.; Bioconjug.Chem., 26:690-698, 2015; PubMed: 25785518; DOI: 10.1021/acs.bioconjchem.5b00021

Experimental method

X-RAY DIFFRACTION (2.3 Å)