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3VT3

Crystal structures of rat VDR-LBD with R270L mutation

Summary for 3VT3
Entry DOI10.2210/pdb3vt3/pdb
Related2ZLC 3VT4 3VT5 3VT6 3VT7 3VT8 3VT9
DescriptorVitamin D3 receptor, COACTIVATOR PEPTIDE DRIP, 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL, ... (6 entities in total)
Functional Keywordstranscription, hormone receptor
Biological sourceRattus norvegicus (rats)
More
Cellular locationNucleus: P13053
Total number of polymer chains2
Total formula weight32692.65
Authors
Nakabayashi, M.,Shimizu, M.,Ikura, T.,Ito, N. (deposition date: 2012-05-19, release date: 2013-05-22, Last modification date: 2023-11-08)
Primary citationNakabayashi, M.,Tsukahara, Y.,Iwasaki-Miyamoto, Y.,Mihori-Shimazaki, M.,Yamada, S.,Inaba, S.,Oda, M.,Shimizu, M.,Makishima, M.,Tokiwa, H.,Ikura, T.,Ito, N.
Crystal structures of hereditary vitamin D-resistant rickets-associated vitamin D receptor mutants R270L and W282R bound to 1,25-dihydroxyvitamin D3 and synthetic ligands.
J.Med.Chem., 56:6745-6760, 2013
Cited by
PubMed: 23944708
DOI: 10.1021/jm400537h
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

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