3VT8

Crystal structures of rat VDR-LBD with W282R mutation

Summary for 3VT8

Entry DOI	10.2210/pdb3vt8/pdb
Related	2ZLC 3VT3 3VT4 3VT5 3VT6 3VT7 3VT9
Descriptor	Vitamin D3 receptor, COACTIVATOR PEPTIDE DRIP, (1R,3R,7E,9beta,17beta)-9-butyl-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-9,10-secoestra-5,7-diene-1,3-diol, ... (4 entities in total)
Functional Keywords	transcription, hormone receptor
Biological source	Rattus norvegicus (rats) More
Cellular location	Nucleus: P13053
Total number of polymer chains	2
Total formula weight	32597.65
Authors	Nakabayashi, M.,Shimizu, M.,Ikura, T.,Ito, N. (deposition date: 2012-05-19, release date: 2013-05-22, Last modification date: 2023-11-08)
Primary citation	Nakabayashi, M.,Tsukahara, Y.,Iwasaki-Miyamoto, Y.,Mihori-Shimazaki, M.,Yamada, S.,Inaba, S.,Oda, M.,Shimizu, M.,Makishima, M.,Tokiwa, H.,Ikura, T.,Ito, N. Crystal structures of hereditary vitamin D-resistant rickets-associated vitamin D receptor mutants R270L and W282R bound to 1,25-dihydroxyvitamin D3 and synthetic ligands. J.Med.Chem., 56:6745-6760, 2013 Cited by PubMed: 23944708 DOI: 10.1021/jm400537h PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation