3VT8
Crystal structures of rat VDR-LBD with W282R mutation
Summary for 3VT8
Entry DOI | 10.2210/pdb3vt8/pdb |
Related | 2ZLC 3VT3 3VT4 3VT5 3VT6 3VT7 3VT9 |
Descriptor | Vitamin D3 receptor, COACTIVATOR PEPTIDE DRIP, (1R,3R,7E,9beta,17beta)-9-butyl-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-9,10-secoestra-5,7-diene-1,3-diol, ... (4 entities in total) |
Functional Keywords | transcription, hormone receptor |
Biological source | Rattus norvegicus (rats) More |
Cellular location | Nucleus: P13053 |
Total number of polymer chains | 2 |
Total formula weight | 32597.65 |
Authors | Nakabayashi, M.,Shimizu, M.,Ikura, T.,Ito, N. (deposition date: 2012-05-19, release date: 2013-05-22, Last modification date: 2023-11-08) |
Primary citation | Nakabayashi, M.,Tsukahara, Y.,Iwasaki-Miyamoto, Y.,Mihori-Shimazaki, M.,Yamada, S.,Inaba, S.,Oda, M.,Shimizu, M.,Makishima, M.,Tokiwa, H.,Ikura, T.,Ito, N. Crystal structures of hereditary vitamin D-resistant rickets-associated vitamin D receptor mutants R270L and W282R bound to 1,25-dihydroxyvitamin D3 and synthetic ligands. J.Med.Chem., 56:6745-6760, 2013 Cited by PubMed: 23944708DOI: 10.1021/jm400537h PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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