3V1S
Scaffold tailoring by a newly detected Pictet-Spenglerase ac-tivity of strictosidine synthase (STR1): from the common tryp-toline skeleton to the rare piperazino-indole framework
Summary for 3V1S
Entry DOI | 10.2210/pdb3v1s/pdb |
Descriptor | Strictosidine synthase, 2-(1H-indol-1-yl)ethanamine (3 entities in total) |
Functional Keywords | strictosidine synthase, alkaloid biosynthesis, strictosidine synthase family, lyase |
Biological source | Rauvolfia serpentina (devilpepper) |
Cellular location | Vacuole: P68175 |
Total number of polymer chains | 2 |
Total formula weight | 71852.31 |
Authors | Wu, F.,Zhu, H.,Sun, L.,Rajendran, C.,Wang, M.,Ren, X.,Panjikar, S.,Cherkasov, A.,Zou, H.,Stoeckigt, J. (deposition date: 2011-12-10, release date: 2012-02-29, Last modification date: 2023-11-08) |
Primary citation | Wu, F.,Zhu, H.,Sun, L.,Rajendran, C.,Wang, M.,Ren, X.,Panjikar, S.,Cherkasov, A.,Zou, H.,Stockigt, J. Scaffold Tailoring by a Newly Detected Pictet-Spenglerase Activity of Strictosidine Synthase: From the Common Tryptoline Skeleton to the Rare Piperazino-indole Framework J.Am.Chem.Soc., 134:1498-1500, 2012 Cited by PubMed: 22229634DOI: 10.1021/ja211524d PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.328 Å) |
Structure validation
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