3UP1
Crystal structure of the unliganded human interleukin-7 receptor extracellular domain
Summary for 3UP1
Entry DOI | 10.2210/pdb3up1/pdb |
Descriptor | Interleukin-7 receptor subunit alpha, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose, ... (7 entities in total) |
Functional Keywords | cytokine receptor, fibronectin type 3 fold, membrane and soluble, glycosylation, immune system |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 53629.05 |
Authors | McElroy, C.A.,Holland, P.J.,Walsh, S.T.R. (deposition date: 2011-11-17, release date: 2012-02-08, Last modification date: 2022-12-21) |
Primary citation | McElroy, C.A.,Holland, P.J.,Zhao, P.,Lim, J.M.,Wells, L.,Eisenstein, E.,Walsh, S.T. Structural reorganization of the interleukin-7 signaling complex. Proc.Natl.Acad.Sci.USA, 109:2503-2508, 2012 Cited by PubMed: 22308406DOI: 10.1073/pnas.1116582109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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