3UKR
Crystal structure of Bos taurus Arp2/3 complex with bound inhibitor CK-666
Summary for 3UKR
Entry DOI | 10.2210/pdb3ukr/pdb |
Related | 3UKU 3ULE |
Descriptor | Actin-related protein 3, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, ... (9 entities in total) |
Functional Keywords | beta-propeller actin fold, structural protein, atp binding |
Biological source | Bos taurus (bovine,cow,domestic cattle,domestic cow) More |
Cellular location | Cytoplasm, cytoskeleton (By similarity): P61157 A7MB62 Q58CQ2 Q3MHR7 Q3T035 Q148J6 Q3SYX9 |
Total number of polymer chains | 7 |
Total formula weight | 224496.91 |
Authors | Nolen, B.J.,Han, M. (deposition date: 2011-11-09, release date: 2013-02-13, Last modification date: 2024-02-28) |
Primary citation | Baggett, A.W.,Cournia, Z.,Han, M.S.,Patargias, G.,Glass, A.C.,Liu, S.Y.,Nolen, B.J. Structural characterization and computer-aided optimization of a small-molecule inhibitor of the Arp2/3 complex, a key regulator of the actin cytoskeleton. Chemmedchem, 7:1286-1294, 2012 Cited by PubMed: 22623398DOI: 10.1002/cmdc.201200104 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.48 Å) |
Structure validation
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