3UBY
Crystal structure of human alklyadenine DNA glycosylase in a lower and higher-affinity complex with DNA
Summary for 3UBY
Entry DOI | 10.2210/pdb3uby/pdb |
Related | 1BNK 1EWN 1F4R 1F6O 3QI5 |
Descriptor | DNA-3-methyladenine glycosylase, DNA (5'-D(*GP*AP*CP*AP*TP*GP*(EDC)P*TP*TP*GP*CP*CP*T)-3') (3 entities in total) |
Functional Keywords | alkyladenine dna glycosylase fold, aag, dna repair, dna binding, nucleus, hydrolase-dna complex, hydrolase/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus (Potential): P29372 |
Total number of polymer chains | 4 |
Total formula weight | 56562.97 |
Authors | Setser, J.W.,Lingaraju, G.M.,Davis, C.A.,Samson, L.D.,Drennan, C.L. (deposition date: 2011-10-25, release date: 2011-12-28, Last modification date: 2023-09-13) |
Primary citation | Setser, J.W.,Lingaraju, G.M.,Davis, C.A.,Samson, L.D.,Drennan, C.L. Searching for DNA lesions: structural evidence for lower- and higher-affinity DNA binding conformations of human alkyladenine DNA glycosylase. Biochemistry, 51:382-390, 2012 Cited by PubMed: 22148158DOI: 10.1021/bi201484k PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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