3UAJ
Crystal structure of the envelope glycoprotein ectodomain from dengue virus serotype 4 in complex with the fab fragment of the chimpanzee monoclonal antibody 5H2
Summary for 3UAJ
Entry DOI | 10.2210/pdb3uaj/pdb |
Related | 3UC0 |
Descriptor | envelope protein, Heavy chain, monoclonal antibody 5H2, Light chain, monoclonal antibody 5H2, ... (4 entities in total) |
Functional Keywords | dengue antibody membrane fusion, viral protein-immune system complex, viral protein/immune system |
Biological source | Dengue virus 4 More |
Total number of polymer chains | 6 |
Total formula weight | 192139.46 |
Authors | Cockburn, J.J.B.,Stura, E.A.,Navarro-Sanchez, M.E.,Rey, F.A. (deposition date: 2011-10-21, release date: 2011-12-14, Last modification date: 2023-09-13) |
Primary citation | Cockburn, J.J.,Navarro Sanchez, M.E.,Goncalvez, A.P.,Zaitseva, E.,Stura, E.A.,Kikuti, C.M.,Duquerroy, S.,Dussart, P.,Chernomordik, L.V.,Lai, C.J.,Rey, F.A. Structural insights into the neutralization mechanism of a higher primate antibody against dengue virus. Embo J., 31:767-779, 2012 Cited by PubMed: 22139356DOI: 10.1038/emboj.2011.439 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.232 Å) |
Structure validation
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